| Ontology Information |
| PRO ID | PR:000000678 |
| PRO name | sodium leak channel non-selective protein |
| Synonyms | NALCN (EXACT)PRO-short-label;
CanIon (EXACT)[DNx];
voltage gated channel-like protein 1 (EXACT);
VGCNL1 (RELATED) |
| Definition | A protein that is a translation product of the NALCN gene or a 1:1 ortholog thereof. The prototype subunit contains four copies of the six transmembrane ion transport protein domain, but the number of copies of this domain varies among splice variants. Responsible for the background sodium ion leak current in neurons and controls neuronal excitability. They are subunits of a voltage-independent, nonselective cation channel. [PMID:17448995, PRO:CNA] |
| Comment | Category=gene. |
Hierarchical relationship
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