| Ontology Information |
| PRO ID | PR:000001423 |
| PRO name | histamine H2 receptor |
| Synonyms | HRH2 (EXACT)PRO-short-label;
gastric receptor I (EXACT);
H2 histamine receptor (EXACT);
H2R (EXACT);
HH2R (EXACT) |
| Definition | A rhodopsin-like G-protein coupled receptor that is a translation product of the HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects. [PMID:9311023, PRO:WCB] |
| Comment | Category=gene. |
Hierarchical relationship
|
Parent: PR:000001094 rhodopsin-like G-protein coupled receptor
Children: none |  | ( click to see DAG view. ) |
|
| This PRO entry has been created based on the following
|
DB name:ID
|
UniProtKB:P25021 |
|
1
101
201
301
|
--------10 --------20 --------30 --------40 --------50 --------60 --------70 --------80 --------90 -------100
MAPNGTASSF CLDSTACKIT ITVVLAVLIL ITVAGNVVVC LAVGLNRRLR NLTNCFIVSL AITDLLLGLL VLPFSAIYQL SCKWSFGKVF CNIYTSLDVM
LCTASILNLF MISLDRYCAV MDPLRYPVLV TPVRVAISLV LIWVISITLS FLSIHLGWNS RNETSKGNHT TSKCKVQVNE VYGLVDGLVT FYLPLLIMCI
TYYRIFKVAR DQAKRINHIS SWKAATIREH KATVTLAAVM GAFIICWFPY FTAFVYRGLR GDDAINEVLE AIVLWLGYAN SALNPILYAA LNRDFRTGYQ
QLFCCRLANR NSHKTSLRSN ASQLSRTQSR EPRQQEEKPL KLQVWSGTEV TAPQGATDR
|
| |
| | Taxon ID |
9606 |
DB name:ID
|
UniProtKB:P97292 |
|
1
101
201
301
|
--------10 --------20 --------30 --------40 --------50 --------60 --------70 --------80 --------90 -------100
MEPNGTVHSC CLDSIALKVT ISVVLTTLIF ITVAGNVVVC LAVSLNRRLR SLTNCFIVSL AATDLLLGLL VMPFSAIYQL SFKWRFGQVF CNIYTSLDVM
LCTASILNLF MISLDRYCAV TDPLRYPVLV TPVRVAISLV FIWVISITLS FLSIHLGWNS RNGTRGGNDT FKCKVQVNEV YGLVDGMVTF YLPLLIMCVT
YYRIFKIARE QAKRINHISS WKAATIREHK ATVTLAAVMG AFIVCWFPYF TAFVYRGLRG DDPVNEVVEG IVLWLGYANS ALNPILYATL NRDFRMAYQQ
LFHCKLASHN SHKTSLRLNN SLLSRSQSRE GRWQEEKPLK LQVWSGTELT HPQGSPVR
|
| |
| | Taxon ID |
10090 |
|
