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HOME / About / Staff Members / Peter B. McGarvey
Peter B. McGarvey, Ph.D
Project Manager and Research Associate Professor
Protein Information Resource
pbm9@georgetown.edu
Primary Expertise
Peter McGarvey, PhD., is Research Associate Professor, Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center (GUMC). Has academic and commercial experience in molecular biology, biotechnology, bioinformatics and software development, and his research interests include genomic and proteomic analysis, biological databases, and data visualization. Currently, Dr. McGarvey helps manage several projects at PIR and GUMC including the CPTAC Data Center, the Georgetown Centers of Excellence in Regulatory Sciences , the Bioinformatics component of the Georgetown-Howard University CTSA , The Protein Information Resource and the UniProt Knowledgebase. Dr. McGarvey has a PhD in Biological Sciences from the University of Michigan and MS in Technology Management from University of Maryland University College.

Affiliated Websites:

CPTAC Data Center
Georgetown CERSI
Georgetown-Howard CTSA
Protein Information Resource
UniProt Knowledgebase

Education
B.S., Chemistry and Biomedical Sciences, Western Michigan University, Kalamazoo, MI. 1979
Ph.D., Biological Sciences, The University of Michigan, Ann Arbor, MI. 1988
M.S., Technology Management,University Maryland University College, College Park, MD. 2004

Professional Activities
Member, American Association for the Advancement of Science. (1995-present).
Editor: Plant Biotechnology: New Products and Applications. Current Topics in Microbiology and Immunology Vol. 240, Springer-Verlag, New York, NY. (1999).
Member Phytonutrient Review Panel, USDA Fund for Rural American (1997).
Institutional Biosafety Committee, Member, Thomas Jefferson University (1995-1998).

Publications
UniProt: a hub for protein information.
UniProt Consortium.
Nucleic Acids Res. Jan 28;43 (Database issue) (2015)
Proteogenomic characterization of human colon and rectal cancer.
Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ, Shaddox KF, Kim S, Davies SR, Wang S, Wang P, Kinsinger CR, Rivers RC, Rodriguez H, Townsend RR, Ellis MJ, Carr SA, Tabb DL, Coffey RJ, Slebos RJ, Liebler DC; NCI CPTAC.
Nature. Sep 18; (2014)
In silico analysis of autoimmune diseases and genetic relationships to vaccination against infectious diseases..
McGarvey PB, Suzek BE, Baraniuk JN, Rao S, Conkright B, Lababidi S, Sutherland A, Forshee R, Madhavan S.
BMC Immunol. 2014 Dec 9;15(1):61. [Epub ahead of print]
UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches.
Suzek BE, Wang Y, Huang H, McGarvey PB, Wu CH; the UniProt Consortium.
Bioinformatics. 2014 Nov 13. pii: btu739. [Epub ahead of print]. PubMed PMID: 25398609.
Reorganizing the protein space at the Universal Protein Resource (UniProt).
UniProt Consortium.
Nucleic Acids Res. 40 (Database issue): D71-5 (2012). PMID: 22102590
Informatics and data quality at collaborative multicenter Breast and Colon Cancer Family Registries.
McGarvey PB, Ladwa S, Oberti M, Dragomir AD, Hedlund EK, Tanenbaum DM, Suzek BE, Madhavan S.
J Am Med Inform Assoc. 2012 Feb 9. [Epub ahead of print] PMID: 22323393.
A comprehensive protein-centric ID mapping service for molecular data integration.
Huang H, McGarvey PB, Suzek BE, Mazumder R, Zhang J, Chen Y, Wu CH.
Bioinformatics. Apr 15;27(8):1190-1.. 2011.
Protein-centric data integration for functional analysis of comparative proteomics data.
McGarvey PB, Zhang J, Natale DA, Wu CH, Huang H.
Methods Mol Biol. 694:323-39. 2011.
Ongoing and future developments at the Universal Protein Resource.
UniProt Consortium.
Nucleic Acids Res. 39(Database issue):D214-9. 2011.
From protein sequences to 3D-structures and beyond: the example of the UniProt knowledgebase.
Hinz U; UniProt Consortium.
Cell Mol Life Sci. 67(7):1049-64. 2010.
Protein Bioinformatics Infrastructure for the Integration and Analysis of Multiple High-Throughput omics Data.
Chen C, McGarvey PB, Huang H, Wu CH.
Adv Bioinformatics. 2010; 2010:423589. 2010.
The Universal Protein Resource (UniProt) in 2010.
UniProt Consortium.
Nucleic Acids Res. 38(Database issue):D142-8. 2010.
Systems integration of biodefense omics data for analysis of pathogen-host interactions and identification of potential targets.
McGarvey PB, Huang H, Mazumder R, Zhang J, Chen Y, Zhang C, Cammer S, Will R, Odle M, Sobral B, Moore M, Wu CH.
PLoS One. 4(9):e7162. 2009.
Infrastructure for the life sciences: design and implementation of the UniProt website.
Jain E, Bairoch A, Duvaud S, Phan I, Redaschi N, Suzek BE, Martin MJ, McGarvey P, Gasteiger E.
BMC Bioinformatics. 10:136. 2009.
The Universal Protein Resource (UniProt) 2009.
UniProt Consortium.
Nucleic Acids Res. 37(Database issue):D169-74. 2009.
Protein Bioinformatics.
McGarvey P, Huang H, Wu CH.
in: Medical Applications of Mass Spectrometry. Part III Biomolecules, Chapter 10:203-222. K Vekey, A Telekes, A Vertes (Eds.) Elsevier Science. 2008.
An emerging cyberinfrastructure for biodefense pathogen and pathogen-host data.
Zhang C, Crasta O, Cammer S, Will R, Kenyon R, Sullivan D, Yu Q, Sun W, Jha R, Liu D, Xue T, Zhang Y, Moore M, McGarvey P, Huang H, Chen Y, Zhang J, Mazumder R, Wu C, Sobral B.
Nucleic Acids Res. 36(Database issue):D884-91. 2008.
UniRef: comprehensive and non-redundant UniProt reference clusters.
Suzek BE, Huang H, McGarvey P, Mazumder R, Wu CH.
Bioinformatics. 23(10):1282-8. 2007.
The Universal Protein Resource (UniProt).
UniProt Consortium.
Nucleic Acids Res. 35(Database issue):D193-7. 2007.
Protein Information Resource: a community resource for expert annotation of protein data.
Barker WC, Garavelli JS, Hou Z, Huang H, Ledley RS, McGarvey PB, Mewes HW, Orcutt BC, Pfeiffer F, Tsugita A, Vinayaka CR, Xiao C, Yeh LS, Wu C.
Nucleic Acids Res. 29(1):29-32. 2001.
PIR: a new resource for bioinformatics.
McGarvey PB, Huang H, Barker WC, Orcutt BC, Garavelli JS, Srinivasarao GY, Yeh LS, Xiao C, Wu CH.
Bioinformatics. 16(3):290-1. 2000.
The protein information resource (PIR).
Barker WC, Garavelli JS, Huang H, McGarvey PB, Orcutt BC, Srinivasarao GY, Xiao C, Yeh LS, Ledley RS, Janda JF, Pfeiffer F, Mewes HW, Tsugita A, Wu C.
Nucleic Acids Res. 28(1):41-4. 2000.
The PIR-International Protein Sequence Database.
Barker WC, Garavelli JS, McGarvey PB, Marzec CR, Orcutt BC, Srinivasarao GY, Yeh LS, Ledley RS, Mewes HW, Pfeiffer F, Tsugita A, Wu C.
Nucleic Acids Res. 27(1):39-43. 1999.
Cucumber mosaic virus from Ixora: infectious RNA transcripts confirm deficiency in satellite support and unusual symptomatology.
Tousignant ME, McGarvey PM, Piazzolla P, Kaper JM.
Res Virol. 147(6):363-73. 1996.
Expression of the rabies virus glycoprotein in transgenic tomatoes.
McGarvey PB, Hammond J, Dienelt MM, Hooper DC, Fu ZF, Dietzschold B, Koprowski H, Michaels FH.
Biotechnology (NY). 13(13):1484-7. 1995.
The complete sequence of a cucumber mosaic virus from Ixora that is deficient in the replication of satellite RNAs.
McGarvey P, Tousignant M, Geletka L, Cellini F, Kaper JM.
J Gen Virol. 76 ( Pt 9):2257-70. 1995.
A simple and rapid method for screening transgenic plants using the PCR.
McGarvey P, Kaper JM.
Biotechniques. 11(4):428-32. 1991.
Transformed tomato plants express a satellite RNA of cucumber mosaic virus and produce lethal necrosis upon infection with viral RNA.
McGarvey PB, Kaper JM, Avila-Rincon MJ, Peņa L, Diaz-Ruiz JR.
Biochem Biophys Res Commun. 170(2):548-55. 1990.
Processing of chloroplast ribosomal RNA transcripts in Euglena gracilis bacillaris. Curr Genet. 1989 May;15(5):363-70.
McGarvey P, Helling RB.
Curr Genet. 15(5):363-70. Erratum in Curr Genet. 16(2):129. 1989.
Initiation of rrn transcription in chloroplasts of Euglena gracilis bacillaris.
McGarvey P, Helling RB, Lee JY, Engelke DR, el-Gewely MR.
Curr Genet. 14(5):493-500. 1988.
Activation of N-hydroxyphenacetin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation.
Vaught JB, McGarvey PB, Lee MS, Garner CD, Wang CY, Linsmaier-Bednar EM, King CM.
Cancer Res. 41(9 Pt 1):3424-9. 1981.


Revised 04/05/2011

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