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HOME / About / Staff Members / Lai-Su L. Yeh
Lai-Su L. Yeh, Ph.D.
Administrative Coordinator
Protein Information Resource
yeh@nbrf.georgetown.edu
Primary Expertise
Dr. Yeh is responsible for sequence classification annotation and alignment curation. She also performs integrity checks between sequence and alignment databases and coordinates the import of JIPID processed sequence entries.

Education
B.S., Chemistry,Taiwan Normal University,Taiwan, 1965
M.S., Organic Chemistry, Sacremento State University Sacremento, CA. 1968
Ph.D., Biochemistry, University of California, Davis, CA. 1979

Publications
Ongoing and future developments at the Universal Protein Resource.
UniProt Consortium.
Nucleic Acids Res. 39(Database issue):D214-9. 2011.
From protein sequences to 3D-structures and beyond: the example of the UniProt knowledgebase.
Hinz U; UniProt Consortium.
Cell Mol Life Sci. 67(7):1049-64. 2010.
Community annotation in biology.
Mazumder R, Natale DA, Julio JA, Yeh LS, Wu CH.
Biol Direct. 5:12. 2010.
The Universal Protein Resource (UniProt) in 2010.
UniProt Consortium.
Nucleic Acids Res. 38(Database issue):D142-8. 2010.
The Universal Protein Resource (UniProt) 2009.
UniProt Consortium.
Nucleic Acids Res. 37(Database issue):D169-74. 2009.
The Universal Protein Resource (UniProt).
UniProt Consortium.
Nucleic Acids Res. 35(Database issue):D193-7. 2007.
The Universal Protein Resource (UniProt).
Bairoch A, Apweiler R, Wu CH, Barker WC, Boeckmann B, Ferro S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Natale DA, O'Donovan C, Redaschi N, Yeh LS.
Nucleic Acids Res. 33(Database issue):D154-9. 2005.
UniProt: the Universal Protein knowledgebase.
Apweiler R, Bairoch A, Wu CH, Barker WC, Boeckmann B, Ferro S, Gasteiger E, Huang H, Lopez R, Magrane M, Martin MJ, Natale DA, O'Donovan C, Redaschi N, Yeh LS.
Nucleic Acids Res. 32(Database issue):D115-9. 2004.
PIRSF: family classification system at the Protein Information Resource.
Wu CH, Nikolskaya A, Huang H, Yeh LS, Natale DA, Vinayaka CR, Hu ZZ, Mazumder R, Kumar S, Kourtesis P, Ledley RS, Suzek BE, Arminski L, Chen Y, Zhang J, Cardenas JL, Chung S, Castro-Alvear J, Dinkov G, Barker WC.
Nucleic Acids Res. 32(Database issue):D112-4. 2004.
Protein family classification and functional annotation.
Wu CH, Huang H, Yeh LS, Barker WC.
Comput Biol Chem. 27(1):37-47. 2003.
The Protein Information Resource.
Wu CH, Yeh LS, Huang H, Arminski L, Castro-Alvear J, Chen Y, Hu Z, Kourtesis P, Ledley RS, Suzek BE, Vinayaka CR, Zhang J, Barker WC.
Nucleic Acids Res. 31(1):345-7. 2003.
The Protein Information Resource: an integrated public resource of functional annotation of proteins.
Wu CH, Huang H, Arminski L, Castro-Alvear J, Chen Y, Hu ZZ, Ledley RS, Lewis KC, Mewes HW, Orcutt BC, Suzek BE, Tsugita A, Vinayaka CR, Yeh LS, Zhang J, Barker WC.
Nucleic Acids Res. 30(1):35-7. 2002.
Protein Information Resource: a community resource for expert annotation of protein data.
Barker WC, Garavelli JS, Hou Z, Huang H, Ledley RS, McGarvey PB, Mewes HW, Orcutt BC, Pfeiffer F, Tsugita A, Vinayaka CR, Xiao C, Yeh LS, Wu C.
Nucleic Acids Res. 29(1):29-32. 2001.
PIR: a new resource for bioinformatics.
McGarvey PB, Huang H, Barker WC, Orcutt BC, Garavelli JS, Srinivasarao GY, Yeh LS, Xiao C, Wu CH.
Bioinformatics. 16(3):290-1. 2000.
The protein information resource (PIR).
Barker WC, Garavelli JS, Huang H, McGarvey PB, Orcutt BC, Srinivasarao GY, Xiao C, Yeh LS, Ledley RS, Janda JF, Pfeiffer F, Mewes HW, Tsugita A, Wu C.
Nucleic Acids Res. 28(1):41-4. 2000.
PIR-ALN: a database of protein sequence alignments.
Srinivasarao GY, Yeh LS, Marzec CR, Orcutt BC, Barker WC.
Bioinformatics. 15(5):382-90. 1999.
Database of protein sequence alignments: PIR-ALN.
Srinivasarao GY, Yeh LS, Marzec CR, Orcutt BC, Barker WC, Pfeiffer F.
Nucleic Acids Res. 27(1):284-5. 1999.
The PIR-International Protein Sequence Database.
Barker WC, Garavelli JS, McGarvey PB, Marzec CR, Orcutt BC, Srinivasarao GY, Yeh LS, Ledley RS, Mewes HW, Pfeiffer F, Tsugita A, Wu C.
Nucleic Acids Res. 27(1):39-43. 1999.
The PIR-International Protein Sequence Database.
Barker WC, Garavelli JS, Haft DH, Hunt LT, Marzec CR, Orcutt BC, Srinivasarao GY, Yeh LS, Ledley RS, Mewes HW, Pfeiffer F, Tsugita A.
Nucleic Acids Res. 26(1):27-32. 1998.
The Protein Information Resource (PIR) and the PIR-International Protein Sequence Database.
George DG, Dodson RJ, Garavelli JS, Haft DH, Hunt LT, Marzec CR, Orcutt BC, Sidman KE, Srinivasarao GY, Yeh LS, Arminski LM, Ledley RS, Tsugita A, Barker WC.
Nucleic Acids Res. 25(1):24-8. 1997.
Non-sequence databases for biological activity and physicochemical properties.
Jone CS, Tsugita A, Satake K, Okibayashi F, Imai K, Yagi T, Takahashi K, Yeh LS.
Protein Seq Data Anal. 4(6):367-74. 1991.
Escherichia coli K12 genomic database.
Kunisawa T, Nakamura M, Watanabe H, Otsuka J, Tsugita A, Yeh LS, George DG, Barker WC.
Protein Seq Data Anal. 3(2):157-62. 1990.
Homologues of catalytic domains of Cellulomonas glucanases found in fungal and Bacillus glycosidases.
West CA, Elzanowski A, Yeh LS, Barker WC.
FEMS Microbiol Lett. 50(1-2):167-72. 1989.
Protein sequence database of the protein identification resource (PIR).
Barker WC, Hunt LT, George DG, Yeh LS, Chen HR, Blomquist MC, Seibel-Ross EI, Elzanowski A, Bair JK, Ferrick DA, et al.
Protein Seq Data Anal. 2(1):39-79. 1989.
Protein Sequence Database of the Protein Identification Resource (PIR).
Barker WC, Hunt LT, George DG, Yeh LS, Chen HR, Blomquist MC, Seibel-Ross EI, Elzanowski A, Bair JK, Ferrick DA, et al.
Protein Seq Data Anal. 1(3):195-250. 1988.
Homology of delta crystallin and argininosuccinate lyase.
Yeh LS, Elzanowski A, Hunt LT, Barker WC.
Comp Biochem Physiol B. 89(2):433-7. 1988.
Protein sequence database of the protein identification resource (PIR).
Barker WC, Hunt LT, George DG, Yeh LS, Chen HR, Blomquist MC, Seibel-Ross EI, Elzanowski A, Bair JK, Ferrick DA, et al.
Protein Seq Data Anal. 1(2):129-75. 1987.
Protein sequence database of the protein identification resource (PIR).
Barker WC, Hunt LT, George DG, Yeh LS, Chen HR, Blomquist MC, Seibel-Ross EI, Elzanowski A, Bair JK, Ferrick DA, et al.
Protein Seq Data Anal. 1(1):43-98. 1987.
Similarity between oncogenic v-rel protein and regulatory fnr protein.
Chen HR, Yeh LS, Barker WC.
Nucleic Acids Res. 14(9):3977. 1986.
New perspectives on bacterial ferredoxin evolution.
George DG, Hunt LT, Yeh LS, Barker WC.
J Mol Evol. 22(1):20-31. 1985.
Identification of the probable coding region for exon 2 of cytochrome oxidase polypeptide I from Aspergillus nidulans mitochondrion.
George DG, Yeh LS, Hunt LT, Barker WC.
Biochem Biophys Res Commun. 119(2):786-94. 1984.
Ragweed allergen Ra3: relationship to some type 1 copper-binding proteins.
Hunt LT, George DG, Yeh LS.
J Mol Evol. 21(2):126-32. 1984.
Evolution of prokaryote and eukaryote lines inferred from sequence evidence.
Hunt LT, George DG, Yeh LS, Dayhoff MO.
Orig Life. 14(1-4):657-64. 1984.
Unexpected relationships between bacteriophage lambda hypothetical proteins and bacteriophage T4 tail-fiber proteins.
George DG, Yeh LS, Barker WC.
Biochem Biophys Res Commun. 115(3):1061-8. 1983.
Nucleic Acid Sequence Database V: completely sequenced genomes.
Chen HR, Dayhoff MO, Barker WC, Hunt LT, Yeh LS, George DG, Orcutt BC.
DNA. 2(4):275-80. 1983.
Nucleic acid sequence database IV.
Chen HR, Dayhoff MO, Barker WC, Hunt LT, Yeh LS, George DG, Orcutt BC.
DNA. 1(4):365-74. 1982.
Nucleic acid sequence database III.
Chen HR, Dayhoff MO, Barker WC, Hunt LT, Yeh LS, George DG, Orcutt BC.
DNA. 1(3):273. 1982.
Sequence bank update. Nucleic acid sequence database II.
Chen HR, Dayhoff MO, Barker WC, Hunt LT, Yeh LS, George DG, Orcutt BC.
DNA. 1(2):103-8. 1982.


Revised 04/06/2011

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